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Nephrology - Dialysis department
Réseau Hospitalier de Médecine Sociale
Belgium
This Website was developped and designed by Dr Debelle. Its content only reflects authors' own view.
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Treatments of chronic kidney diseases
According to the origin of the chronic kidney disease (diabetes mellitus, hypertension, glomerulonephritis, polycystic kidney disease, chronic pyelonephritis, toxic origin,...), several actions should be taken in order to slow down the progression of the renal dysfunction

A tight control of all cardiovascular risk factors is necessary  (hypertension, diabetes, obesity, hypercholesterolemia, smoking, sedentary lifestyle...). Among them, the blood pressure must be maintained below 130/80 mmHg, or even below 125/80 mmHg for diabetic patients. Specific antihypertensive medications (called "ACE inhibitor" or "sartan") are been proven to effectively slow down the progression of kidney disease. This therapy requires a steadily control of your blood pressure and your blood test (because of the higher risk to temporarily exacerbate the renal insufficiency and to increase the blood level of the potassium). Your general practitioner or your nephrologist will give you all information you need.

            Specific treatments will be started according to the type of your kidney disease. For example, medications such as immunosuppressive agents (steroid therapy,...) are effective on some kidney disease called "glomerulonephritis".

Prophylactic actions are the cornerstone  of kidney diseases. Indeed, several drugs may be deleterious in case of renal disease. Non steroidal anti-inflammatory drugs (NSAID) such as ibuprofen, diclofenac, piroxicam, naproxen... have a significant toxicity on the kidneys. Although these medications are available over-the-counter, it would be better to  ask the opinion of your doctor.

Important note: If you have a CT scan or a magnetic resonance imaging (MRI),  you must inform your doctor and the radiologist that you suffer from kidney disease. Indeed, a higher risk for toxicity complications may be seen when iodinated or gadolinium-based contrasts are infused.